Concepedia

David B. Shackelford

DB

34

Publications

9.8K

Citations

27

H-Index

2006

Active since

Affiliations

University of California, Los Angeles(Current)

UCLA Jonsson Comprehensive Cancer Center

VA Greater Los Angeles Healthcare System

Salk Institute for Biological Studies

David B. Shackelford is an author at University of California, Los Angeles specializing in medicine, cell biology, and tumor biology.

Top concepts

MedicineCell BiologyTumor BiologyBiochemistryPharmacologyCell SignalingCancer ResearchCancer MetabolismRadiation OncologySignal Transduction

Publications per year

2006–2025

34

Publications

34

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Dana M. Gwinn, David B. Shackelford, Daniel F. Egan et al. · Molecular Cell · 2008 · 3.7K citations · Full text

Signal Transduction, Signaling Pathway, Metabolic Checkpoint +5

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Daniel F. Egan, David B. Shackelford, Maria M. Mihaylova et al. · Science · 2010 · 2.5K citations

Mitophagy, Environmental Stress, Cell Death +18

Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent

Dane M. Wolf, Mayuko Segawa, Arun Kumar Kondadi et al. · The EMBO Journal · 2019 · 309 citations · Full text

Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1α

Brandon Faubert, Emma E. Vincent, Takla Griss et al. · Proceedings of the National Academy of Sciences · 2014 · 281 citations · Full text

Extracellular Matrix Remodeling Regulates Glucose Metabolism through TXNIP Destabilization

William J. Sullivan, Peter Mullen, E. Schmid et al. · Cell · 2018 · 258 citations · Full text

Txnip Destabilization, Signal Transduction, Metabolic Regulation +5

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