María E. Figueroa

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

María E. Figueroa, Omar Abdel‐Wahab, Chao Lü et al. · Cancer Cell · 2010 · 2.7K citations · Full text

Medicine, Genetics, Hematology +17

methylKit: a comprehensive R package for the analysis of genome-wide DNA methylation profiles

Altuna Akalin, Matthías Kormáksson, Sheng Li et al. · Genome biology · 2012 · 2.4K citations · Full text

Medicine, Bioinformatics, Molecular Biology +17

IDH mutation impairs histone demethylation and results in a block to cell differentiation

Chao Lü, Patrick S. Ward, Gurpreet S. Kapoor et al. · Nature · 2012 · 2K citations

Life Sciences, Genetics, Molecular Biology +14

Prognostic Relevance of Integrated Genetic Profiling in Acute Myeloid Leukemia

Jay P. Patel, Mithat Gönen, María E. Figueroa et al. · New England Journal of Medicine · 2012 · 1.9K citations · Full text

Life Sciences, Genetics, Oncology +16

Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation

Kelly Moran-Crusio, Linsey B. Reavie, Alan H. Shih et al. · Cancer Cell · 2011 · 1.3K citations · Full text

Life Sciences, Cell Biology, Hematology +13