Chao Lü

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

María E. Figueroa, Omar Abdel‐Wahab, Chao Lü et al. · Cancer Cell · 2010 · 2.7K citations · Full text

Medicine, Genetics, Hematology +17

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

Şevin Turcan, Daniel Rohle, Anuj Goenka et al. · Nature · 2012 · 2K citations · Full text

Medicine, Cancer Biology, Oncology +14

IDH mutation impairs histone demethylation and results in a block to cell differentiation

Chao Lü, Patrick S. Ward, Gurpreet S. Kapoor et al. · Nature · 2012 · 2K citations

Life Sciences, Genetics, Molecular Biology +14

Metabolic Regulation of Epigenetics

Chao Lü, Craig B. Thompson · Cell Metabolism · 2012 · 679 citations · Full text

Life Sciences, Biology, Molecular Biology +7

The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape

Daniel N. Weinberg, Simon Papillon‐Cavanagh, Haifeng Chen et al. · Nature · 2019 · 563 citations · Full text

Life Sciences, Genetics, Molecular Biology +12