Chao Lü

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

María E. Figueroa, Omar Abdel‐Wahab, Chao Lü et al. · Cancer Cell · 2010 · 2.7K citations · Full text

Hematological Malignancy, Somatic Variant, Hypermethylation Phenotype +10

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype

Şevin Turcan, Daniel Rohle, Anuj Goenka et al. · Nature · 2012 · 1.9K citations · Full text

Neuro-oncology, Somatic Variant, Tumor Heterogeneity +11

IDH mutation impairs histone demethylation and results in a block to cell differentiation

Chao Lü, Patrick S. Ward, Gurpreet S. Kapoor et al. · Nature · 2012 · 1.9K citations

Histone Modifications, Epigenetic Change, Genetics +17

Metabolic Regulation of Epigenetics

Chao Lü, Craig B. Thompson · Cell Metabolism · 2012 · 657 citations · Full text

Chromatin, Medicine, Genetics +9

The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape

Daniel N. Weinberg, Simon Papillon‐Cavanagh, Haifeng Chen et al. · Nature · 2019 · 545 citations · Full text

Histone Modifications, Chromatin, Chromatin Remodeling +10