Alan H. Shih

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

María E. Figueroa, Omar Abdel‐Wahab, Chao Lü et al. · Cancer Cell · 2010 · 2.7K citations · Full text

Hematological Malignancy, Somatic Variant, Hypermethylation Phenotype +10

Tet2 Loss Leads to Increased Hematopoietic Stem Cell Self-Renewal and Myeloid Transformation

Kelly Moran-Crusio, Linsey B. Reavie, Alan H. Shih et al. · Cancer Cell · 2011 · 1.3K citations · Full text

Developmental Biology, Medicine, Stem Cell Mobilization +8

ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression

Omar Abdel‐Wahab, Mazhar Adli, Lindsay M. LaFave et al. · Cancer Cell · 2012 · 585 citations · Full text

Hematological Malignancy, Chromatin, Somatic Variant +8

TET2 and TET3 regulate GlcNAcylation and H3K4 methylation through OGT and SET1/COMPASS

Rachel Deplus, Benjamin Delatte, Marie K. Schwinn et al. · The EMBO Journal · 2013 · 486 citations · Full text

Chromatin, Signal Transduction, Biochemistry +8

The function of PML in p53-dependent apoptosis

Ailan Guo, Paolo Salomoni, Jianyuan Luo et al. · Nature Cell Biology · 2000 · 468 citations

P53-dependent Apoptosis, Apoptosis, Cell Death +4