Xun Bao

Oncometabolites suppress DNA repair by disrupting local chromatin signalling

Parker L. Sulkowski, Sebastian Oeck, Jonathan Dow et al. · Nature · 2020 · 293 citations · Full text

Chromatin, Genome Instability, Dna Damage +9

Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair

Parker L. Sulkowski, Ranjini K. Sundaram, Sebastian Oeck et al. · Nature Genetics · 2018 · 212 citations

Chromatin, Genome Instability, Dna Damage +12

Protein Expression and Functional Relevance of Efflux and Uptake Drug Transporters at the Blood–Brain Barrier of Human Brain and Glioblastoma

Xun Bao, Jianmei Wu, Youming Xie et al. · Clinical Pharmacology & Therapeutics · 2019 · 85 citations · Full text

Bbb Transporter Abundances, Neurochemical Biomarkers, High-grade Gliomas +17

A Phase 0 Trial of Ribociclib in Recurrent Glioblastoma Patients Incorporating a Tumor Pharmacodynamic- and Pharmacokinetic-Guided Expansion Cohort

An‐Chi Tien, Jing Li, Xun Bao et al. · Clinical Cancer Research · 2019 · 79 citations

Quantitative and Mechanistic Understanding of AZD1775 Penetration across Human Blood–Brain Barrier in Glioblastoma Patients Using an IVIVE–PBPK Modeling Approach

Jing Li, Jianmei Wu, Xun Bao et al. · Clinical Cancer Research · 2017 · 62 citations · Full text