Sebastian Oeck

Oncometabolites suppress DNA repair by disrupting local chromatin signalling

Parker L. Sulkowski, Sebastian Oeck, Jonathan Dow et al. · Nature · 2020 · 293 citations · Full text

Chromatin, Genome Instability, Dna Damage +9

Krebs-cycle-deficient hereditary cancer syndromes are defined by defects in homologous-recombination DNA repair

Parker L. Sulkowski, Ranjini K. Sundaram, Sebastian Oeck et al. · Nature Genetics · 2018 · 212 citations

Chromatin, Genome Instability, Dna Damage +12

Cediranib suppresses homology-directed DNA repair through down-regulation of BRCA1/2 and RAD51

Alanna R. Kaplan, Susan E. Gueble, Yanfeng Liu et al. · Science Translational Medicine · 2019 · 147 citations

Mitochondrial DNA stress signalling protects the nuclear genome

Zheng Wu, Sebastian Oeck, A. Phillip West et al. · Nature Metabolism · 2019 · 129 citations · Full text

Chromatin, Mitochondrial Biogenesis, Mitochondrial Function +7

Hypoxia Induces Resistance to EGFR Inhibitors in Lung Cancer Cells via Upregulation of FGFR1 and the MAPK Pathway

Yuhong Lü, Yanfeng Liu, Sebastian Oeck et al. · Cancer Research · 2020 · 113 citations · Full text