A. Phillip West

Mitochondrial DNA stress primes the antiviral innate immune response

A. Phillip West, William Khoury-Hanold, Matthew Staron et al. · Nature · 2015 · 1.8K citations · Full text

Inflammation, Autoimmune Disease, Mitochondrial Function +8

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

A. Phillip West, Igor E. Brodsky, Christoph Rahner et al. · Nature · 2011 · 1.6K citations · Full text

Inflammation, Toll-like Receptors, Innate Immune System +7

Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA

Anthony Rongvaux, Ruaidhrí Jackson, Christian C. D. Harman et al. · Cell · 2014 · 799 citations · Full text

Apoptotic Caspases Prevent, Mitochondrial Function, Mitochondrial Dynamic +8

A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1

Baoyu Zhao, Fenglei Du, Pengbiao Xu et al. · Nature · 2019 · 394 citations · Full text

Transcriptional Regulation, Signal Transduction, Signaling Pathway +9

Mitochondrial ROS promotes susceptibility to infection via gasdermin D-mediated necroptosis

Chi G. Weindel, E. Martínez, Xiao Zhao et al. · Cell · 2022 · 349 citations · Full text

Inflammation, Mitophagy, Mitochondrial Function +8