Igor E. Brodsky

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

A. Phillip West, Igor E. Brodsky, Christoph Rahner et al. · Nature · 2011 · 1.6K citations · Full text

Inflammation, Toll-like Receptors, Innate Immune System +7

NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8

Isabella Rauch, Katherine A. Deets, Daisy X. Ji et al. · Immunity · 2017 · 405 citations · Full text

Inflammation, Mucosal Immunology, Immunology +9

A Yersinia Effector Protein Promotes Virulence by Preventing Inflammasome Recognition of the Type III Secretion System

Igor E. Brodsky, Noah W. Palm, Saheli Sadanand et al. · Cell Host & Microbe · 2010 · 303 citations · Full text

Protein Secretion, Virulence Factor, Inflammasome Recognition +10

Caspase-8 mediates caspase-1 processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling

Naomi H. Philip, Christopher P. Dillon, Annelise G. Snyder et al. · Proceedings of the National Academy of Sciences · 2014 · 279 citations · Full text

Microbial Pathogens, Innate Immune System, Immunology +25

Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity

Denise Morais da Fonseca, Timothy W. Hand, Seong‐Ji Han et al. · Cell · 2015 · 279 citations · Full text

Host Response, Microbiota-dependent Sequelae, Immunology +3