Wei Xu

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

Wei Xu, Hui Yang, Ying Liu et al. · Cancer Cell · 2011 · 2.8K citations · Full text

Life Sciences, Biochemistry, Pharmacology +8

Regulation of Cellular Metabolism by Protein Lysine Acetylation

Shimin Zhao, Wei Xu, Wenqing Jiang et al. · Science · 2010 · 1.9K citations

Life Sciences, Biochemistry, Molecular Biology +15

Glioma-Derived Mutations in <i>IDH1</i> Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1α

Shimin Zhao, Yan Lin, Wei Xu et al. · Science · 2009 · 1.1K citations

Medicine, Molecular Biology, Oncology +17

AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

Shrivani Sriskanthadevan, Danny V. Jeyaraju, Timothy Chung et al. · Blood · 2015 · 342 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +17

SIRT5 Desuccinylates and Activates Pyruvate Kinase M2 to Block Macrophage IL-1β Production and to Prevent DSS-Induced Colitis in Mice

Fang Wang, Ke Wang, Wei Xu et al. · Cell Reports · 2017 · 342 citations · Full text

Life Sciences, Cell Biology, Immunology +17