Shimin Zhao

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

Wei Xu, Hui Yang, Ying Liu et al. · Cancer Cell · 2011 · 2.8K citations · Full text

Life Sciences, Biochemistry, Pharmacology +8

PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase

Gommaar D’Hulst, Inés Soro-Arnáiz, Evi Masschelein et al. · Nature Communications · 2020 · 2.3K citations · Full text

Life Sciences, Biochemistry, Physiology +17

Regulation of Cellular Metabolism by Protein Lysine Acetylation

Shimin Zhao, Wei Xu, Wenqing Jiang et al. · Science · 2010 · 1.9K citations

Life Sciences, Biochemistry, Molecular Biology +15

Glioma-Derived Mutations in <i>IDH1</i> Dominantly Inhibit IDH1 Catalytic Activity and Induce HIF-1α

Shimin Zhao, Yan Lin, Wei Xu et al. · Science · 2009 · 1.1K citations

Medicine, Molecular Biology, Oncology +17

Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux

Qijun Wang, Yakun Zhang, Chen Yang et al. · Science · 2010 · 999 citations · Full text

Life Sciences, Biochemistry, Enzymology +11