Danny V. Jeyaraju

Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia

Alicia M. Cole, Zezhou Wang, Étienne Coyaud et al. · Cancer Cell · 2015 · 349 citations · Full text

Medicine, Oncology, Pharmacology +9

AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress

Shrivani Sriskanthadevan, Danny V. Jeyaraju, Timothy Chung et al. · Blood · 2015 · 342 citations · Full text

Life Sciences, Cancer Biology, Cell Biology +17

A Mitofusin-2–dependent inactivating cleavage of Opa1 links changes in mitochondria <i>cristae</i> and ER contacts in the postprandial liver

Aditi Sood, Danny V. Jeyaraju, Julien Prudent et al. · Proceedings of the National Academy of Sciences · 2014 · 173 citations · Full text

Life Sciences, Cell Biology, Physiology +17

Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphology

Danny V. Jeyaraju, Liqun Xu, Marie-Claude Letellier et al. · Proceedings of the National Academy of Sciences · 2006 · 95 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Preclinical evaluation of the selective small-molecule UBA1 inhibitor, TAK-243, in acute myeloid leukemia

Samir H. Barghout, Parasvi S. Patel, Xiaoming Wang et al. · Leukemia · 2018 · 90 citations

Medicine, Oncology, Pharmacology +8