Samir H. Barghout

Mitochondrial ClpP-Mediated Proteolysis Induces Selective Cancer Cell Lethality

Jo Ishizawa, Sarah F. Zarabi, R. Eric Davis et al. · Cancer Cell · 2019 · 339 citations · Full text

Preclinical evaluation of the selective small-molecule UBA1 inhibitor, TAK-243, in acute myeloid leukemia

Samir H. Barghout, Parasvi S. Patel, Xiaoming Wang et al. · Leukemia · 2018 · 84 citations

Hematological Malignancy, Preclinical Evaluation, Acute Myeloid Leukemia +10

Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal

Rashim Pal Singh, Danny V. Jeyaraju, Véronique Voisin et al. · Cell stem cell · 2020 · 53 citations · Full text

Mitochondrial Function, Medicine, Stem Cell Research +4

A genome-wide CRISPR/Cas9 screen in acute myeloid leukemia cells identifies regulators of TAK-243 sensitivity

Samir H. Barghout, Kazem Nouri, Zachary Blatman et al. · JCI Insight · 2021 · 49 citations · Full text

Engineering, Mixed-phenotype Acute Leukemia, Genetics +21

Elevated β-catenin activity contributes to carboplatin resistance in A2780cp ovarian cancer cells

Samir H. Barghout, Nubia Zepeda, Zhihua Xu et al. · Biochemical and Biophysical Research Communications · 2015 · 41 citations

Oncology, Medicine, β-Catenin Activity Contributes +7