Concepedia

Therapeutic base editing of human hematopoietic stem cells

Jing Zeng, Yuxuan Wu, Chunyan Ren, Jasmine Bonanno, Anne H. Shen, Devlin Shea, Jason M. Gehrke, Kendell Clement, Kevin Luk, Qiuming Yao,

Nature Medicine · 2020 · 280 citations · 31 references

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References

31

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Alexis C. Komor, Y. Bill Kim, Michael S. Packer et al. · Nature · 2016 · 5.4K citations · Full text

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Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

Adam Siepel, Gill Bejerano, Jakob Skou Pedersen et al. · Genome Research · 2005 · 4.3K citations · Full text

, , +17

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

Nicole M. Gaudelli, Alexis C. Komor, Holly A. Rees et al. · Nature · 2017 · 4.2K citations · Full text

, , +12

Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases

Sangsu Bae, Jeongbin Park, Jin‐Soo Kim · Bioinformatics · 2014 · 2.4K citations · Full text

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Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems

Keiji Nishida, Takayuki Arazoe, Nozomu Yachie et al. · Science · 2016 · 1.4K citations

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