Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9

Yuxuan Wu, Dan Liang, Yinghua Wang, +6

Cell stem cell

Highly efficient therapeutic gene editing of human hematopoietic stem cells

Yuxuan Wu, Jing Zeng, Benjamin P. Roscoe, +21

Nature Medicine

Induced Pluripotent Stem CellGenome SurgeryMedicineStem Cell MobilizationStem Cell Research +5

An APOBEC3A-Cas9 base editor with minimized bystander and off-target activities

Jason M. Gehrke, Oliver Cervantes, Kendell Clement, +5

Nature Biotechnology

Apobec3a-cas9 Base Editor

Non-viral, specifically targeted CAR-T cells achieve high safety and efficacy in B-NHL

Jiqin Zhang, Yongxian Hu, Jiaxuan Yang, +19

Nature

Formation of hierarchical Bi2MoO6/ln2S3 S-scheme heterojunction with rich oxygen vacancies for boosting photocatalytic CO2 reduction

Bo Yu, Yuxuan Wu, Fanming Meng, +7

Chemical Engineering Journal

Materials SciencePhotocatalytic Co2 ReductionEngineeringPhotoredox ProcessPhotochemistry +8

Dual base editor catalyzes both cytosine and adenine base conversions in human cells

Xiaohui Zhang, Biyun Zhu, Liang Chen, +23

Nature Biotechnology

Cellular EnzymologyBiochemistryAdenine Base ConversionsHuman CellsNatural Sciences +9

Therapeutic base editing of human hematopoietic stem cells

Jing Zeng, Yuxuan Wu, Chunyan Ren, +13

Nature Medicine

Regenerative MedicineTherapeutic Base EditingMedicineStem Cell MobilizationCell Replacement Therapy +4

Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells

Yuxuan Wu, Hai Zhou, Xiaoying Fan, +19

Cell Research

SpermatogenesisGeneticsGenetic EngineeringStem Cell ResearchGenetic Disease +7

Genome editing of HBG1 and HBG2 to induce fetal hemoglobin

Jean‐Yves Métais, Phillip A. Doerfler, Thiyagaraj Mayuranathan, +24

Blood Advances

CRISPR–Cas9-mediated gene editing of the BCL11A enhancer for pediatric β0/β0 transfusion-dependent β-thalassemia

Bin Fu, Jiaoyang Liao, Shuanghong Chen, +13

Nature Medicine

Gene TherapiesGeneticsHematologyGenetic EngineeringGene Editing +7