UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9

Xiaoli Liu, Qinqin Gao, Pishun Li, +5

Nature Communications

Histone ModificationsChromatinChromatin RemodelingHemi-methylated DnaGenetics +11

Non-viral, specifically targeted CAR-T cells achieve high safety and efficacy in B-NHL

Jiqin Zhang, Yongxian Hu, Jiaxuan Yang, +19

Nature

S phase-dependent interaction with DNMT1 dictates the role of UHRF1 but not UHRF2 in DNA methylation maintenance

Jiqin Zhang, Qinqin Gao, Pishun Li, +7

Cell Research

Histone ModificationsChromatinGenome InstabilityChromatin RemodelingEpigenetic Change +9

Dissecting the precise role of H3K9 methylation in crosstalk with DNA maintenance methylation in mammals

Qian Zhao, Jiqin Zhang, Ruoyu Chen, +13

Nature Communications

Histone ModificationsHistone H3k9 MethylationEpigenetic ChangeGeneticsDna Methylation +23

Genetic correction of β-thalassemia patient-specific iPS cells and its use in improving hemoglobin production in irradiated SCID mice

Yixuan Wang, Chenguang Zheng, Yonghua Jiang, +9

Cell Research

Irradiated Scid MiceImmunohematologyLaboratory HematologyGeneticsHemoglobin Production +7

EGFR regulates iron homeostasis to promote cancer growth through redistribution of transferrin receptor 1

Biao Wang, Jiqin Zhang, Fei Song, +11

Cancer Letters

Cancer ResearchCell RegulationIron MetabolismMedicineIron Homeostasis +8

EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer

Jiqin Zhang, Fei Song, Xiaojing Zhao, +11

Molecular Cancer

ASK1-dependent endothelial cell activation is critical in ovarian cancer growth and metastasis

Mingzhu Yin, Huanjiao Jenny Zhou, Jiqin Zhang, +8

JCI Insight

An Elaborate Regulation of Mammalian Target of Rapamycin Activity Is Required for Somatic Cell Reprogramming Induced by Defined Transcription Factors

Jing He, Lan Kang, Tong Wu, +9

Stem Cells and Development

Elaborate RegulationMolecular RegulationRapamycin ActivityTranscriptional RegulationSignaling Pathway +20

Interleukin‑22 regulates the homeostasis of the intestinal epithelium during inflammation

Xinyan Zhang, Shijie Liu, Yueqian Wang, +7

International Journal of Molecular Medicine

ImmunologyGastroenterologyPathologyImmune RegulationImmunologic Mechanism +21