Concepedia

Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction

Xindong Liu, Yun Wang, Huiping Lu, Jing Li, Xiaowei Yan, Minglu Xiao, Jing Hao, Andrei Alekseev, Hiep Khong, Tenghui Chen,

Nature · 2019 · 528 citations · 23 references

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23

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

Warren A. Whyte, David A. Orlando, Denes Hnisz et al. · Cell · 2013 · 4.3K citations · Full text

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Super-Enhancers in the Control of Cell Identity and Disease

Denes Hnisz, Brian J. Abraham, Tong Ihn Lee et al. · Cell · 2013 · 3.9K citations · Full text

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Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

Kristen E. Pauken, Morgan A. Sammons, Pamela M. Odorizzi et al. · Science · 2016 · 1.3K citations

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Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells

Gang Wei, Lai Wei, Jinfang Zhu et al. · Immunity · 2009 · 1.2K citations · Full text

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The epigenetic landscape of T cell exhaustion

Debattama R. Sen, James J. Kaminski, R. Anthony Barnitz et al. · Science · 2016 · 958 citations · Full text

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