Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

Laurie A. Boyer, Tong Ihn Lee, Megan F. Cole, +11

Cell

Transcriptional RegulationDevelopmental BiologyMedicineAdult Stem CellStem Cell Research +4

Super-Enhancers in the Control of Cell Identity and Disease

Denes Hnisz, Brian J. Abraham, Tong Ihn Lee, +5

Cell

Cell RegulationAutoimmunityCell IdentityMedicineCell Biology +2

Transcriptional Regulatory Networks in <i>Saccharomyces cerevisiae</i>

Tong Ihn Lee, Nicola J. Rinaldi, François Robert, +18

Science

GeneticsGene Regulatory NetworkGene TranscriptionTranscriptional RegulationMetabolic Network +18

Coactivator condensation at super-enhancers links phase separation and gene control

Benjamin R. Sabari, Alessandra Dall’Agnese, Ann Boija, +20

Science

EngineeringCoactivator IdrsMolecular BiologyGene Regulatory NetworkProtein Phase Separation +15

Polycomb complexes repress developmental regulators in murine embryonic stem cells

Laurie A. Boyer, Kathrin Plath, Julia Zeitlinger, +13

Nature

Lineage PlasticityDevelopmental BiologyMedicineStem Cell ResearchCell Fate Determination +5

Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells

Tong Ihn Lee, Richard G. Jenner, Laurie A. Boyer, +25

Cell

Developmental RegulatorsInduced Pluripotent Stem CellEmbryonic Stem CellDevelopmental BiologyCell Specialization +7

Transcriptional regulatory code of a eukaryotic genome

Christopher Harbison, D. Benjamin Gordon, Tong Ihn Lee, +17

Nature

Transcriptional RegulationGeneticsGene StructureGene Regulatory NetworkGene Transcription +6

Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains

Ann Boija, Isaac A. Klein, Benjamin R. Sabari, +16

Cell

ChromatinTranscriptional RegulationFunctional GenomicsPhase-separation CapacityMolecular Regulation +11

Dissecting the Regulatory Circuitry of a Eukaryotic Genome

Frank C. P. Holstege, Ezra G. Jennings, John J. Wyrick, +6

Cell

Functional GenomicsRegulatory CircuitryGeneticsGenomic MechanismGene Structure +5

Transcriptional Amplification in Tumor Cells with Elevated c-Myc

Charles Y. Lin, Jakob Lovén, Peter B. Rahl, +5

Cell

Tumor BiologyCell RegulationOncogenic AgentMedicineElevated C-myc +3