RNA N6‐methyladenosine methyltransferase‐like 3 promotes liver cancer progression through YTHDF2‐dependent posttranscriptional silencing of SOCS2

Mengnuo Chen, Lai Wei, Cheuk‐Ting Law, +10

Hepatology

Generation of pathogenic TH17 cells in the absence of TGF-β signalling

Kamran Ghoreschi, Arian Laurence, Xiang‐Ping Yang, +18

Nature

InflammationTgf-β SignallingImmunologyPathologyAutoimmunity +9

Global Mapping of H3K4me3 and H3K27me3 Reveals Specificity and Plasticity in Lineage Fate Determination of Differentiating CD4+ T Cells

Gang Wei, Lai Wei, Jinfang Zhu, +13

Immunity

ChromatinLineage PlasticityCell LineageDevelopmental BiologyH3k27me3 Reveals Specificity +9

COVID-19 immune features revealed by a large-scale single-cell transcriptome atlas

Xianwen Ren, Wen Wen, Xiaoying Fan, +87

Cell

Single Cell SequencingMedicineImmunologySingle-cell GenomicsChronic Viral Infection +3

Epidemiologic and Clinical Characteristics of Novel Coronavirus Infections Involving 13 Patients Outside Wuhan, China

De Chang, Minggui Lin, Lai Wei, +4

JAMA

Virus EpidemiologyCase SeriesCovid-19 EpidemiologyPatient Hospital DataCovid-19 +17

Diverse Targets of the Transcription Factor STAT3 Contribute to T Cell Pathogenicity and Homeostasis

Lydia Durant, Wendy T. Watford, Haydeé L. Ramos, +8

Immunity

Transcriptional RegulationAutoimmune DiseaseAdaptive Immune SystemT-regulatory CellImmunology +11

IL-21 Is Produced by Th17 Cells and Drives IL-17 Production in a STAT3-dependent Manner

Lai Wei, Arian Laurence, Kevin M. Elias, +1

Journal of Biological Chemistry

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

Xiang‐Ping Yang, Kamran Ghoreschi, Scott Steward-Tharp, +10

Nature Immunology

InflammationCytokineImmune Cell DevelopmentImmunologyImmune Regulation +6

Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction

Xindong Liu, Yun Wang, Huiping Lu, +26

Nature

Signal TransductionAutoimmune DiseaseT Cell DysfunctionT-regulatory CellImmunology +6

Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC

Lai Wei, Derek Lee, Cheuk‐Ting Law, +9

Nature Communications