Proteolysis of methylated SOX2 protein is regulated by L3MBTL3 and CRL4DCAF5 ubiquitin ligase

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Tissue Engineering, Regenerative Medicine, Defined Factors +14

Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

Laurie A. Boyer, Tong Ihn Lee, Megan F. Cole et al. · Cell · 2005 · 4.4K citations · Full text

Transcriptional Regulation, Developmental Biology, Medicine +6

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells

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Embryonic Stem Cell, Induced Pluripotent Stem Cell, Developmental Biology +8

Dissecting self-renewal in stem cells with RNA interference

Natalia Ivanova, Radu Dobrin, Rong Lu et al. · Nature · 2006 · 959 citations

Medicine, Adult Stem Cell, Stem Cell Research +3

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

Jing Wang, Sarah Hevi, Julia K. Kurash et al. · Nature Genetics · 2008 · 806 citations

Chromatin, Chromatin Remodeling, Epigenetic Change +10