Concepedia

The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation

Jing Wang, Sarah Hevi, Julia K. Kurash, Hong Lei, Frédérique Gay, Jeffrey Bajko, Hui Su, Weitao Sun, Hua Chang, Guoliang Xu,

Nature Genetics · 2008 · 813 citations · 25 references

DOI

Concepts

References

25

DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

Masaki Okano, Daphne W. Bell, Daniel A. Haber et al. · Cell · 1999 · 6.1K citations · Full text

, , +15

Histone Demethylation Mediated by the Nuclear Amine Oxidase Homolog LSD1

Yujiang Geno Shi, Yujiang Geno Shi, Fei Lan et al. · Cell · 2004 · 4K citations · Full text

, , +11

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

En Li, Timothy H. Bestor, Rudolf Jaenisch · Cell · 1992 · 4K citations

, , +14

The Polycomb group protein EZH2 directly controls DNA methylation

Emmanuelle Viré, Carmen Brenner, Rachel Deplus et al. · Nature · 2005 · 2.2K citations

, , +14

LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription

Eric Metzger, Melanie Wissmann, Na Yin et al. · Nature · 2005 · 1.7K citations

, , +12