Dna Methylation

DNA Methylation is a biochemical process in which a methyl group is covalently added to the cytosine base of DNA, typically at cytosine-guanine dinucleotide sites, thereby altering gene expression without changing the underlying DNA sequence.

20K

Publications

1.7M

Citations

80.1K

Authors

8.4K

Institutions

Publications per year

2017–2026

5.1K

Variants

Dna Methylation Analysis

Parents

EpigeneticsGenomic Data AnalysisMolecular PathologyTranscriptional Regulation

Children

Active Dna DemethylationCell-type Specific MethylationDifferential Methylation AnalysisDifferentially Methylated RegionsDna MethyltransferasesGene Body MethylationGlobal Dna MethylationMethylation ArraysMethylation QuantificationMethylation Variability

Publications

20K

DNA methylation age of human tissues and cell types

Steve Horvath · Genome biology · 2013 · 7.3K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

<i>MGMT</i> Gene Silencing and Benefit from Temozolomide in Glioblastoma

Monika E. Hegi, Annie‐Claire Diserens, Thierry Gorlia et al. · New England Journal of Medicine · 2005 · 7.3K citations · Full text

Medicine, Molecular Biology, Oncology +17

DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development

Masaki Okano, Daphne W. Bell, Daniel A. Haber et al. · Cell · 1999 · 6.1K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +15

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications

Felix Krueger, Simon Andrews · Bioinformatics · 2011 · 5.9K citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +16

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

Mamta Tahiliani, Kian Peng Koh, Yinghua Shen et al. · Science · 2009 · 5.8K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

1–5 of 20K

Authors

80.1K

SE
Steven E. Jacobsen
University of California, Los Angeles, United States
89 publications · 27.9K citations
72
h-index
JJ
Jean‐Pierre J. Issa
The University of Texas MD Anderson Cancer Center, United States
88 publications · 20.3K citations
64
h-index
ME
Manel Esteller
Institut d'Investigació Biomédica de Bellvitge, Spain
100 publications · 25.2K citations
63
h-index
MS
Moshe Szyf
McGill University, Canada
110 publications · 12.3K citations
63
h-index
PA
Peter A. Jones
University of Southern California, United States
87 publications · 19.5K citations
62
h-index

1–5 of 80.1K

Institutions

8.4K

1–8 of 8.4K

Venues

Proceedings of the National Academy of Sciences
PNAS · 454 publications · 88.1K citations
157
h-index
Nucleic Acids Research
862 publications · 82.5K citations
133
h-index
Journal of Biological Chemistry
JBC · 632 publications · 55.5K citations
126
h-index
Nature
177 publications · 92.6K citations
123
h-index
PubMed
Repository · 578 publications · 47.9K citations
114
h-index

1–5