Kian Peng Koh

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

Mamta Tahiliani, Kian Peng Koh, Yinghua Shen et al. · Science · 2009 · 5.8K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

Myunggon Ko, Yun Huang, A. Jankowska et al. · Nature · 2010 · 1.3K citations

Medicine, Cancer Biology, Oncology +16

Tet1 and Tet2 Regulate 5-Hydroxymethylcytosine Production and Cell Lineage Specification in Mouse Embryonic Stem Cells

Kian Peng Koh, Akiko Yabuuchi, Sridhar Rao et al. · Cell stem cell · 2011 · 784 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

Bernard Thienpont, Jessica Steinbacher, Hui Zhao et al. · Nature · 2016 · 668 citations · Full text

Medicine, Cancer Biology, Molecular Biology +16

Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening

Matteo Boretto, Nina Maenhoudt, Xinlong Luo et al. · Nature Cell Biology · 2019 · 501 citations

Medicine, Gynecology, Pharmacology +9