Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

Mamta Tahiliani, Kian Peng Koh, Yinghua Shen, +8

Science

Human DNA methylomes at base resolution show widespread epigenomic differences

Ryan Lister, Mattia Pelizzola, Robert H. Dowen, +15

Nature

ChromatinHuman Dna MethylomesChromatin RemodelingEpigenetic ChangeGenetics +8

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

Shinsuke Ito, Ana C. D’Alessio, Olena Taranova, +3

Nature

Signal TransductionCell RegulationMolecular BiologyTet ProteinsProtein Transport +7

Mutation in <i>TET2</i> in Myeloid Cancers

François Delhommeau, Sabrina Dupont, Véronique Della Valle, +20

New England Journal of Medicine

Induction of Tumors in Mice by Genomic Hypomethylation

François Gaudet, John Hodgson, Amir Eden, +5

Science

Tumor BiologyGenome InstabilityChromatinEpigenetic ChangeGenetics +12

Acquired mutations in TET2 are common in myelodysplastic syndromes

Saskia Langemeijer, Roland P. Kuiper, M Berends, +15

Nature Genetics

Hematological MalignancyGenetic DisorderMedicineGeneticsHematology +4

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

Omar Abdel‐Wahab, Ann Mullally, Cyrus V. Hedvat, +21

Blood

The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing

Yun Huang, William A. Pastor, Yinghua Shen, +3

PLoS ONE

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction

Ann-Marie E Bröske, Lena Vockentanz, Shabnam Kharazi, +12

Nature Genetics

ChromatinMedicineGeneticsDna MethylationEpigenetic Change +8

TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis

Ayalew Tefferi, Animesh Pardanani, Ken‐Hong Lim, +15

Leukemia

Hematological MalignancyPolycythemia VeraBone Marrow FailureMalignant Blood DisorderHematology +8