Concepedia

Proteolytic Enzymes

Proteolytic Enzymes is a subclass of hydrolases characterized by their specific catalytic function in cleaving peptide bonds within proteins, thereby facilitating the proteolytic degradation of polypeptide chains.

50.4K

Publications

3M

Citations

131.5K

Authors

10.1K

Institutions

Publications per year

2017–2026

4.6K

Variants

PeptidasesProteasesProteinases

Parents

Children

Publications

50.4K

Peptide mapping by limited proteolysis in sodium dodecyl sulfate and analysis by gel electrophoresis.

Don W. Cleveland, S G Fischer, Marc W. Kirschner et al. · Journal of Biological Chemistry · 1977 · 5.6K citations · Full text

, , +17

On the size of the active site in proteases. I. Papain

Israël Schechter, Arieh Berger · Biochemical and Biophysical Research Communications · 1967 · 5.2K citations

, , +9

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry et al. · Nature · 1995 · 4K citations

, , +13

β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

Robert Vassar, Brian D. Bennett, Safura Babu‐Khan et al. · Science · 1999 · 3.8K citations · Full text

, , +17

The preparation and properties of two new chromogenic substrates of trypsin

Bernard F. Erlanger, Nicholas Kokowsky, William Cohen · Archives of Biochemistry and Biophysics · 1961 · 3.4K citations

, , +4

1–5 of 50.4K

Authors

131.5K

  1. AL
    Alfred L. Goldberg

    Harvard University, United States

    161 publications · 30.4K citations

    98

    h-index

  2. AJ
    A. John Barrett

    National Heart Lung and Blood Institute, United States

    112 publications · 19.8K citations

    64

    h-index

  3. NG
    Nabil G. Seidah

    Montreal Clinical Research Institute, Canada

    133 publications · 11.7K citations

    59

    h-index

  4. CS
    Charles S. Craik

    University of California, San Francisco, United States

    128 publications · 10.7K citations

    58

    h-index

  5. RT
    Robert T. Sauer

    Massachusetts Institute of Technology, United States

    90 publications · 10.4K citations

    57

    h-index

1–5 of 131.5K

Institutions

10.1K

  1. Harvard University

    Cambridge, United States

    171 h-index

    2.7K publications

    389.5K citations

  2. University of California, San Francisco

    San Francisco, United States

    124 h-index

    2K publications

    204.4K citations

  3. National Institutes of Health

    Bethesda, United States

    119 h-index

    1.7K publications

    153.3K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    108 h-index

    996 publications

    140.5K citations

  5. Max Planck Institute of Biochemistry

    Martinsried, Germany

    101 h-index

    970 publications

    117.5K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    97 h-index

    2.7K publications

    152.5K citations

  7. Washington University in St. Louis

    St Louis, United States

    97 h-index

    941 publications

    130.8K citations

  8. Brigham and Women's Hospital

    Boston, United States

    91 h-index

    731 publications

    106.2K citations

1–8 of 10.1K

Venues

  1. Journal of Biological Chemistry

    JBC · 5.4K publications · 489.7K citations

    258

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 1.1K publications · 160.7K citations

    212

    h-index

  3. Biochemical Journal

    BJ · 1.3K publications · 78.8K citations

    129

    h-index

  4. Biochemistry

    1.4K publications · 81.3K citations

    124

    h-index

  5. The EMBO Journal

    201 publications · 37.5K citations

    115

    h-index

1–5