Concepedia
Statistics
Publications
125
Citations
27.4K
H-Index
66
Active since
1986
Affiliations
Merck Canada Inc. (Canada)(Current)
Merck & Co., Inc., Rahway, NJ, USA (United States)
University of British Columbia
McGill University
Ludwig-Maximilians-Universität München
Donald W. Nicholson is an author at Merck Canada Inc. (Canada) specializing in medicine, cell biology, and cell death.
Top concepts
MedicineCell BiologyCell DeathCell SignalingNatural SciencesSignal TransductionBiochemistryCellular BiochemistryApoptosisImmunology
Publications per year
1986–2012
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry et al. · Nature · 1995 · 4K citations
Protein Function, Biochemistry, Ice/ced-3 Protease +11
A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B
Nancy A. Thornberry, Thomas A. Rano, Erin P. Peterson et al. · Journal of Biological Chemistry · 1997 · 2.1K citations · Full text
Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner
Elizabeth A. Slee, Mary T. Harte, Ruth M. Kluck et al. · The Journal of Cell Biology · 1999 · 1.9K citations · Full text
Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors
Margarita García‐Calvo, Erin P. Peterson, Barbara Leiting et al. · Journal of Biological Chemistry · 1998 · 985 citations · Full text
Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation
François G. Gervais, Daigen Xu, George S. Robertson et al. · Cell · 1999 · 785 citations · Full text
Neurodegenerative Diseases, Protein Function, Alzheimer's Disease +11
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