Concepedia

Cysteine Proteases

Cysteine Protease is a type of proteolytic enzyme that catalyzes the hydrolysis of peptide bonds using a nucleophilic cysteine residue within its active site, distinguishing it from other proteases by the critical role of the thiol group in the catalytic mechanism.

4.8K

Publications

314.9K

Citations

17.8K

Authors

3.1K

Institutions

Publications per year

2017–2026

464

Variants

Cysteine PeptidasesThiol Proteases

Parents

Publications

4.8K

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nancy A. Thornberry, Herbert G. Bull, Jimmy Calaycay et al. · Nature · 1992 · 2.6K citations

, , +12

The <i>α</i>/<i>β</i> hydrolase fold

David L. Ollis, Eong Cheah, Mirosław Cygler et al. · Protein Engineering Design and Selection · 1992 · 2.1K citations · Full text

, , +17

A Combinatorial Approach Defines Specificities of Members of the Caspase Family and Granzyme B

Nancy A. Thornberry, Thomas A. Rano, Erin P. Peterson et al. · Journal of Biological Chemistry · 1997 · 2.1K citations · Full text

, , +14

The cysteine switch: a principle of regulation of metalloproteinase activity with potential applicability to the entire matrix metalloproteinase gene family.

Harold E. Van Wart, Henning Birkedal‐Hansen · Proceedings of the National Academy of Sciences · 1990 · 1.5K citations

, , +16

Cysteine cathepsins: From structure, function and regulation to new frontiers

Vito Türk, Veronika Stoka, Olga Vasiljeva et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 2011 · 1.4K citations · Full text

, , +17

1–5 of 4.8K

Authors

17.8K

  1. JH
    James H. McKerrow

    University of California, San Francisco, United States

    72 publications · 6.6K citations

    48

    h-index

  2. VT
    Vito Türk

    Jožef Stefan Institute, Slovenia

    90 publications · 8K citations

    47

    h-index

  3. MA
    Magnus Abrahamson

    Lund University, Sweden

    58 publications · 5K citations

    43

    h-index

  4. MB
    Matthew Bogyo

    Stanford University, United States

    48 publications · 6.9K citations

    38

    h-index

  5. AJ
    A. John Barrett

    National Heart Lung and Blood Institute, United States

    46 publications · 6.8K citations

    37

    h-index

1–5 of 17.8K

Institutions

3.1K

  1. University of California, San Francisco

    San Francisco, United States

    70 h-index

    486 publications

    62.1K citations

  2. Jožef Stefan Institute

    Ljubljana, Slovenia

    56 h-index

    431 publications

    38.8K citations

  3. Lund University

    Lund, Sweden

    51 h-index

    231 publications

    21.9K citations

  4. Harvard University

    Cambridge, United States

    49 h-index

    346 publications

    48.1K citations

  5. Inserm

    Paris, France

    38 h-index

    303 publications

    21.7K citations

  6. University of California San Diego

    San Diego, United States

    35 h-index

    199 publications

    10.4K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    34 h-index

    206 publications

    11.1K citations

  8. National Institutes of Health

    Bethesda, United States

    34 h-index

    218 publications

    18.8K citations

1–8 of 3.1K

Venues

  1. Journal of Biological Chemistry

    JBC · 360 publications · 44.5K citations

    118

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 91 publications · 19.1K citations

    74

    h-index

  3. Biochemical Journal

    BJ · 166 publications · 10.1K citations

    57

    h-index

  4. FEBS Letters

    155 publications · 8.8K citations

    57

    h-index

  5. PubMed

    Repository · 176 publications · 10K citations

    55

    h-index

1–5