β-Casein micelles for oral delivery of SN-38 and elacridar to overcome BCRP-mediated multidrug resistance in gastric cancer

A standardised static<i>in vitro</i>digestion method suitable for food – an international consensus

Mans Minekus, Marie Alminger, Paula Alvito et al. · Food & Function · 2014 · 5.5K citations · Full text

Agriculture, Food Science, Nutritional Sciences +6

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

Y H Hsiang, Robert Hertzberg, Sidney M. Hecht et al. · Journal of Biological Chemistry · 1985 · 2.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata^1,2

Monroe E. Wall, Mansukh C. Wani, Clarence Cook et al. · Journal of the American Chemical Society · 1966 · 2.2K citations

Medicine, Medicinal Chemistry, Pharmacology +8

A graphic method for the determination and presentation of binding parameters in a complex system

Hannah Rosenthal · Analytical Biochemistry · 1967 · 1.5K citations

Pharmacy, Biophysics, Chemistry +13

Subcellular localization and distribution of the breast cancer resistance protein transporter in normal human tissues.

Marc Maliepaard, George L. Scheffer, Ian F. Faneyte et al. · PubMed · 2001 · 1.1K citations

Medicine, Cancer Biology, Oncology +14