Concepedia

Sidney M. Hecht

SM

Statistics

Publications

372

Citations

20.8K

H-Index

68

Active since

1966

Affiliations

University of Virginia(Current)

Arizona State University

BioEnergetics (United States)

Massachusetts Institute of Technology

University of Wisconsin–Madison

Sidney M. Hecht is an author at University of Virginia specializing in life sciences, molecular biology, and biochemistry.

ORCID

Publications per year

1966–2023

372

Publications

372

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.

Y H Hsiang, Robert Hertzberg, Sidney M. Hecht et al. · Journal of Biological Chemistry · 1985 · 2.4K citations · Full text

, , +15

On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

Robert Hertzberg, Mary Jo Caranfa, Sidney M. Hecht · Biochemistry · 1989 · 552 citations

, , +10

Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

William D. Kingsbury, Jeffrey C. Boehm, Dalia R. Jakas et al. · Journal of Medicinal Chemistry · 1991 · 516 citations

, , +10

gamma Ray induced deoxyribonucleic acid strand breaks. 3' Glycolate termini.

W. David Henner, Luis O. Rodriguez, Sidney M. Hecht et al. · Journal of Biological Chemistry · 1983 · 322 citations · Full text

, , +16

The chemistry of activated bleomycin

Sidney M. Hecht · Accounts of Chemical Research · 1986 · 287 citations

, , +6

1–5 of 372