Concepedia

Mary Jo Caranfa

MJ

10

Publications

2.2K

Citations

10

H-Index

1982

Active since

Affiliations

New Frontier(Current)

Hahnemann University Hospital

GlaxoSmithKline (Netherlands)

Mary Jo Caranfa is an author at New Frontier specializing in medicine, natural sciences, and molecular biology.

Top concepts

Publications per year

1982–1993

10

Publications

10

On the mechanism of topoisomerase I inhibition by camptothecin: evidence for binding to an enzyme-DNA complex

Robert Hertzberg, Mary Jo Caranfa, Sidney M. Hecht · Biochemistry · 1989 · 551 citations

Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

William D. Kingsbury, Jeffrey C. Boehm, Dalia R. Jakas et al. · Journal of Medicinal Chemistry · 1991 · 516 citations

, , +16

Modification of the hydroxylactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

Robert Hertzberg, Mary Jo Caranfa, Kenneth G. Holden et al. · Journal of Medicinal Chemistry · 1989 · 411 citations

The inophyllums, novel inhibitors of HIV-1 reverse transcriptase isolated from the Malaysian tree, Calophyllum inophyllum Linn

Ashok D. Patil, Alan J. Freyer, Drake S. Eggleston et al. · Journal of Medicinal Chemistry · 1993 · 408 citations · Full text

, , +20

Camptothecin-resistant mutants of Chinese hamster ovary cells containing a resistant form of topoisomerase I.

R S Gupta, Rajan Gupta, Barry Eng et al. · PubMed · 1988 · 125 citations

, , +12

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