Kenneth G. Holden

Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

William D. Kingsbury, Jeffrey C. Boehm, Dalia R. Jakas et al. · Journal of Medicinal Chemistry · 1991 · 516 citations

Pharmaceutical Science, Antitumor Activity, Altmetric Attention Score +16

Modification of the hydroxylactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

Robert Hertzberg, Mary Jo Caranfa, Kenneth G. Holden et al. · Journal of Medicinal Chemistry · 1989 · 411 citations

<b>The Synthesis of Prodigiosin</b>

Henry Rapoport, Kenneth G. Holden · Journal of the American Chemical Society · 1962 · 178 citations

Altmetrics, Biosynthesis, Quantitative Methods +15

Pyrrolo[1,4]benzodiazepine antitumor antibiotics: relationship of DNA alkylation and sequence specificity to the biological activity of natural and synthetic compounds

Laurence H. Hurley, Teri Reck, David E. Thurston et al. · Chemical Research in Toxicology · 1988 · 139 citations

Identification and quantitation of alditol acetates of neutral and amino sugars from mucins by automated gas-liquid chromatography

Lee J. Griggs, Alex Post, E. RODERICK WHITE et al. · Analytical Biochemistry · 1971 · 110 citations

Alditol Acetates, Biochemistry, Gas Chromatography +10