Dalia R. Jakas

Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

William D. Kingsbury, Jeffrey C. Boehm, Dalia R. Jakas et al. · Journal of Medicinal Chemistry · 1991 · 516 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Modification of the hydroxylactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

Robert Hertzberg, Mary Jo Caranfa, Kenneth G. Holden et al. · Journal of Medicinal Chemistry · 1989 · 414 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Indole Naphthyridinones as Inhibitors of Bacterial Enoyl-ACP Reductases FabI and FabK

Mark A. Seefeld, William H. Miller, Kenneth A. Newlander et al. · Journal of Medicinal Chemistry · 2003 · 161 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Defining and Combating the Mechanisms of Triclosan Resistance in Clinical Isolates of<i>Staphylococcus aureus</i>

Frank Fan, Kang Yan, Nicola G. Wallis et al. · Antimicrobial Agents and Chemotherapy · 2002 · 97 citations · Full text

Life Sciences, Microbiology, Pharmacology +16

Potent, Selective, Orally Active 3-Oxo-1,4-benzodiazepine GPIIb/IIIa Integrin Antagonists

James M. Samanen, Fadia E. Ali, Linda S. Barton et al. · Journal of Medicinal Chemistry · 1996 · 72 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8