Frank Fan

New insights into the genetic etiology of Alzheimer’s disease and related dementias

Céline Bellenguez, Fahri Küçükali, Iris E. Jansen et al. · Nature Genetics · 2022 · 2.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Engineered Luciferase Reporter from a Deep Sea Shrimp Utilizing a Novel Imidazopyrazinone Substrate

Mary P. Hall, James Unch, Brock F. Binkowski et al. · ACS Chemical Biology · 2012 · 1.7K citations · Full text

Life Sciences, Biochemistry, Biotechnology +13

Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in patients with relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b/2 open-label study

Jesús G. Berdeja, Deepu Madduri, Saad Z. Usmani et al. · The Lancet · 2021 · 1.7K citations

Medicine, Hematology, Oncology +17

Generation and expansion of highly pure motor neuron progenitors from human pluripotent stem cells

Zhongwei Du, Hong Chen, Huisheng Liu et al. · Nature Communications · 2015 · 480 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17

Quantitative, Wide-Spectrum Kinase Profiling in Live Cells for Assessing the Effect of Cellular ATP on Target Engagement

James D. Vasta, Cesear Corona, Jennifer Wilkinson et al. · Cell chemical biology · 2017 · 293 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14