Yehuda G. Assaraf

Molecular basis of bortezomib resistance: proteasome subunit β5 (PSMB5) gene mutation and overexpression of PSMB5 protein

Ruud Oerlemans, N. Franke, Yehuda G. Assaraf et al. · Blood · 2008 · 449 citations

Life Sciences, Biochemistry, Molecular Biology +13

Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2.

Jan Hendrik Hooijberg, Henk J. Broxterman, Marcel Kool et al. · PubMed · 1999 · 445 citations

Medicine, Oncology, Pharmacology +17

Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance

Kristy J. Gotink, Henk J. Broxterman, Mariëtte Labots et al. · Clinical Cancer Research · 2011 · 340 citations · Full text

Medicine, Oncology, Pharmacology +14

Lysosomal sequestration of hydrophobic weak base chemotherapeutics triggers lysosomal biogenesis and lysosome-dependent cancer multidrug resistance

Benny Zhitomirsky, Yehuda G. Assaraf · Oncotarget · 2014 · 222 citations · Full text

Medicine, Molecular Biology, Pharmacology +17

The Role of Passive Transbilayer Drug Movement in Multidrug Resistance and Its Modulation

Gera D. Eytan, Ronit Regev, Galit Oren et al. · Journal of Biological Chemistry · 1996 · 182 citations · Full text

Medicine, Pharmacology, Biochemical Pharmacology +16