Jan Hendrik Hooijberg

Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2.

Jan Hendrik Hooijberg, Henk J. Broxterman, Marcel Kool et al. · PubMed · 1999 · 445 citations

Medicine, Oncology, Pharmacology +17

Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies.

George L. Scheffer, Marcel Kool, Marc Heijn et al. · PubMed · 2000 · 210 citations

Life Sciences, Molecular Biology, Pharmacology +11

Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia

Róbert de Jonge, Wim J. E. Tissing, Jan Hendrik Hooijberg et al. · Blood · 2008 · 157 citations · Full text

Life Sciences, Genetics, Pediatrics +12

The Human Multidrug Resistance Protein MRP5 Transports Folates and Can Mediate Cellular Resistance against Antifolates

Peter R. Wielinga, Jan Hendrik Hooijberg, Sjöfn Gunnarsdottir et al. · Cancer Research · 2005 · 138 citations · Full text

Medicine, Biochemistry, Pharmacology +14

Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia

Róbert de Jonge, Jan Hendrik Hooijberg, Bertrand D. van Zelst et al. · Blood · 2005 · 130 citations · Full text

Medicine, Genetics, Molecular Genetics +16