Ruud Oerlemans

Molecular basis of bortezomib resistance: proteasome subunit β5 (PSMB5) gene mutation and overexpression of PSMB5 protein

Ruud Oerlemans, N. Franke, Yehuda G. Assaraf et al. · Blood · 2008 · 442 citations

Effect of age on functional P-glycoprotein in the blood-brain barrier measured by use of (R)-[11C]verapamil and positron emission tomography

Rolf Toornvliet, B.N. vanBerckel, Gert Luurtsema et al. · Clinical Pharmacology & Therapeutics · 2006 · 183 citations

Folate receptor β as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients

Joost W van der Heijden, Ruud Oerlemans, Ben A. C. Dijkmans et al. · Arthritis & Rheumatism · 2008 · 153 citations

Inactivating PSMB5 Mutations and P-Glycoprotein (Multidrug Resistance-Associated Protein/ATP-Binding Cassette B1) Mediate Resistance to Proteasome Inhibitors: Ex Vivo Efficacy of (Immuno)Proteasome Inhibitors in Mononuclear Blood Cells from Patients with Rheumatoid Arthritis

Sue Ellen Verbrugge, Yehuda G. Assaraf, Ben A. C. Dijkmans et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 107 citations

Sulfasalazine is a potent inhibitor of the reduced folate carrier: Implications for combination therapies with methotrexate in rheumatoid arthritis

Gerrit Jansen, Joost van der Heijden, Ruud Oerlemans et al. · Arthritis & Rheumatism · 2004 · 101 citations · Full text