Joost W van der Heijden

Molecular basis of bortezomib resistance: proteasome subunit β5 (PSMB5) gene mutation and overexpression of PSMB5 protein

Ruud Oerlemans, N. Franke, Yehuda G. Assaraf et al. · Blood · 2008 · 449 citations

Life Sciences, Biochemistry, Molecular Biology +13

Folate receptor β as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients

Joost W van der Heijden, Ruud Oerlemans, Ben A. C. Dijkmans et al. · Arthritis & Rheumatism · 2008 · 156 citations

Medicine, Immunology, Pharmacology +17

Noninvasive imaging of macrophages in rheumatoid synovitis using ¹¹C‐(<i>R</i>)‐PK11195 and positron emission tomography

Conny J. van der Laken, Ernst H. Elzinga, Mark A. Kropholler et al. · Arthritis & Rheumatism · 2008 · 111 citations

Medicine, Clinical Sciences, Nuclear Medicine +17

Inactivating PSMB5 Mutations and P-Glycoprotein (Multidrug Resistance-Associated Protein/ATP-Binding Cassette B1) Mediate Resistance to Proteasome Inhibitors: Ex Vivo Efficacy of (Immuno)Proteasome Inhibitors in Mononuclear Blood Cells from Patients with Rheumatoid Arthritis

Sue Ellen Verbrugge, Yehuda G. Assaraf, Ben A. C. Dijkmans et al. · Journal of Pharmacology and Experimental Therapeutics · 2012 · 107 citations

Medicine, Pharmacology, Pharmacotherapy +11

Involvement of breast cancer resistance protein expression on rheumatoid arthritis synovial tissue macrophages in resistance to methotrexate and leflunomide

Joost W van der Heijden, Ruud Oerlemans, Paul P. Tak et al. · Arthritis & Rheumatism · 2009 · 66 citations

Medicine, Immunology, Pharmacology +15