Concepedia

Publication | Closed Access

Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS

DOI

175

Citations

40

References

2017

Year

Sarah J. Ross, Alexey S. Revenko, Lyndsey Hanson, Rebecca Ellston, Anna D. Staniszewska, Nicky Whalley, Sanjay K. Pandey, Mitchell Revill, Claire Rooney, Linda K. Buckett,
Science Translational Medicine

Abstract

AZD4785 is a therapeutic antisense oligonucleotide targeting KRAS mRNA with promising preclinical antitumor activity and a favorable safety profile.

References

YearCitations

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