Concepedia

Antiproliferative Agents

Antiproliferative Agents is a class of immunosuppressive drugs that inhibit lymphocyte proliferation by interfering with DNA synthesis or cell cycle progression, thereby preventing T-cell and B-cell expansion in response to alloantigen stimulation following kidney transplantation.

10.6K

Publications

507.3K

Citations

52.4K

Authors

6.5K

Institutions

Publications per year

2017–2026

3.3K

Variants

Antiproliferatives

Parents

Publications

10.6K

Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate

Gail D. Lewis Phillips, Guangmin Li, Debra L. Dugger et al. · Cancer Research · 2008 · 1.7K citations

, , +17

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

Barry J. Sugarman, Bharat B. Aggarwal, Philip E. Hass et al. · Science · 1985 · 1.6K citations

, , +8

Discovery of <i>N</i>-(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays

Louis J. Lombardo, Francis Y. Lee, Ping Chen et al. · Journal of Medicinal Chemistry · 2004 · 1.3K citations · Full text

, , +13

Specific inhibition of cyclin-dependent kinase 4/6 by PD 0332991 and associated antitumor activity in human tumor xenografts

David W. Fry, Patricia J. Harvey, Paul R. Keller et al. · Molecular Cancer Therapeutics · 2004 · 1.2K citations

, , +16

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.

Mary Ann Jordan, Robert Toso, Douglas Thrower et al. · Proceedings of the National Academy of Sciences · 1993 · 1.1K citations · Full text

, , +17

1–5 of 10.6K

Authors

52.4K

  1. EH
    Ernest Hamel

    National Cancer Institute, United States

    44 publications · 2.5K citations

    29

    h-index

  2. JW
    Joanna Wietrzyk

    Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, Poland

    79 publications · 2.4K citations

    28

    h-index

  3. IZ
    István Zupkó

    University of Szeged, Hungary

    59 publications · 2K citations

    28

    h-index

  4. IO
    Ingo Ott

    Technische Universität Braunschweig, Germany

    32 publications · 2.7K citations

    27

    h-index

  5. JE
    João Ernesto de Carvalho

    Universidade Estadual de Campinas (UNICAMP), Brazil

    51 publications · 2K citations

    27

    h-index

1–5 of 52.4K

Institutions

6.5K

  1. Centre National de la Recherche Scientifique

    Paris, France

    59 h-index

    1.4K publications

    68.2K citations

  2. Inserm

    Paris, France

    57 h-index

    857 publications

    55.2K citations

  3. National Cancer Institute

    Bethesda, United States

    52 h-index

    370 publications

    24.9K citations

  4. The University of Texas MD Anderson Cancer Center

    Houston, United States

    47 h-index

    389 publications

    51.1K citations

  5. National Institutes of Health

    Bethesda, United States

    44 h-index

    297 publications

    23.5K citations

  6. University of Naples Federico II

    Naples, Italy

    43 h-index

    500 publications

    23.8K citations

  7. Harvard University

    Cambridge, United States

    42 h-index

    341 publications

    25.4K citations

  8. Chinese Academy of Sciences

    Beijing, China

    39 h-index

    630 publications

    20.9K citations

1–8 of 6.5K

Venues

  1. Journal of Medicinal Chemistry

    613 publications · 41.3K citations

    103

    h-index

  2. PubMed

    Repository · 745 publications · 43.5K citations

    100

    h-index

  3. Molecular Cancer Therapeutics

    MCT · 155 publications · 12.9K citations

    67

    h-index

  4. European Journal of Medicinal Chemistry

    296 publications · 11.9K citations

    58

    h-index

  5. Cancer Research

    102 publications · 13.3K citations

    57

    h-index

1–5