Ping Chen

Discovery of <i>N</i>-(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays

Louis J. Lombardo, Francis Y. Lee, Ping Chen et al. · Journal of Medicinal Chemistry · 2004 · 1.3K citations · Full text

Drug Target, Preclinical Assays, Pharmacotherapy +19

Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance

Ping Chen, Nathan V. Lee, Wenyue Hu et al. · Molecular Cancer Therapeutics · 2016 · 414 citations

Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1

Alessandra Blasina, Jill Hallin, Enhong Chen et al. · Molecular Cancer Therapeutics · 2008 · 226 citations · Full text

Molecular Biology, Cell Death, Cell Cycle +16

Implications for Chk1 Regulation: The 1.7 Å Crystal Structure of Human Cell Cycle Checkpoint Kinase Chk1

Ping Chen, Chun Luo, Yali Deng et al. · Cell · 2000 · 192 citations · Full text

Signal Transduction, å Crystal Structure, Cell Division +8

Curcumin overcome primary gefitinib resistance in non-small-cell lung cancer cells through inducing autophagy-related cell death

Ping Chen, Hanpeng Huang, Yì Wáng et al. · Journal of Experimental & Clinical Cancer Research · 2019 · 156 citations · Full text