Kevin Ryan

Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK)

J. Jean Cui, Michelle Tran‐Dubé, Hong Shen et al. · Journal of Medicinal Chemistry · 2011 · 922 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19

Robert L. Hoffman, Robert S. Kania, Mary A. Brothers et al. · Journal of Medicinal Chemistry · 2020 · 533 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +15

Rolling Circle DNA Synthesis:  Small Circular Oligonucleotides as Efficient Templates for DNA Polymerases

Dongyu Liu, Sarah L. Daubendiek, Martin A. Zillman et al. · Journal of the American Chemical Society · 1996 · 422 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +15

Symplekin and xGLD-2 Are Required for CPEB-Mediated Cytoplasmic Polyadenylation

Daron Barnard, Kevin Ryan, James L. Manley et al. · Cell · 2004 · 331 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Melanoma mouse model implicates metabotropic glutamate signaling in melanocytic neoplasia

Pamela M. Pollock, Karine Cohen-Solal, Raman Sood et al. · Nature Genetics · 2003 · 295 citations

Veterinary Medicine, Neuroscience, Oncology +16