Hong Shen

Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK)

J. Jean Cui, Michelle Tran‐Dubé, Hong Shen et al. · Journal of Medicinal Chemistry · 2011 · 922 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Localization of PEPT1 and PEPT2 proton-coupled oligopeptide transporter mRNA and protein in rat kidney

Hong Shen, David E. Smith, Tianxin Yang et al. · American Journal of Physiology-Renal Physiology · 1999 · 206 citations

Life Sciences, Biochemistry, Molecular Biology +12

Design of Potent and Selective Inhibitors to Overcome Clinical Anaplastic Lymphoma Kinase Mutations Resistant to Crizotinib

Qinhua Huang, Ted W. Johnson, Simon Bailey et al. · Journal of Medicinal Chemistry · 2014 · 118 citations · Full text

Medicine, Oncology, Pharmacology +14

Developmental Expression of PEPT1 and PEPT2 in Rat Small Intestine, Colon, and Kidney

Hong Shen, David E. Smith, Frank C. Brosius · Pediatric Research · 2001 · 110 citations · Full text

Life Sciences, Molecular Biology, Physiology +14

Differentiation therapy for hepatocellular carcinoma: Multifaceted effects of miR‐148a on tumor growth and phenotype and liver fibrosis

Kwang Hwa Jung, Jing Zhang, Chong Zhou et al. · Hepatology · 2015 · 110 citations · Full text

Medicine, Molecular Biology, Oncology +17