Hong Shen

Structure Based Drug Design of Crizotinib (PF-02341066), a Potent and Selective Dual Inhibitor of Mesenchymal–Epithelial Transition Factor (c-MET) Kinase and Anaplastic Lymphoma Kinase (ALK)

J. Jean Cui, Michelle Tran‐Dubé, Hong Shen et al. · Journal of Medicinal Chemistry · 2011 · 905 citations · Full text

Drug Target, Lead Series, Chemical Biology +20

Localization of PEPT1 and PEPT2 proton-coupled oligopeptide transporter mRNA and protein in rat kidney

Hong Shen, David E. Smith, Tianxin Yang et al. · American Journal of Physiology-Renal Physiology · 1999 · 206 citations

Design of Potent and Selective Inhibitors to Overcome Clinical Anaplastic Lymphoma Kinase Mutations Resistant to Crizotinib

Qinhua Huang, Ted W. Johnson, Simon Bailey et al. · Journal of Medicinal Chemistry · 2014 · 115 citations · Full text

Aminopyridine 8E, Tumor Biology, Kinase Domain +14

Developmental Expression of PEPT1 and PEPT2 in Rat Small Intestine, Colon, and Kidney

Hong Shen, David E. Smith, Frank C. Brosius · Pediatric Research · 2001 · 109 citations · Full text

Developmental Biology, Developmental Expression, Physiology +5

Differentiation therapy for hepatocellular carcinoma: Multifaceted effects of miR‐148a on tumor growth and phenotype and liver fibrosis

Kwang Hwa Jung, Jing Zhang, Chong Zhou et al. · Hepatology · 2015 · 108 citations · Full text