Qinhua Huang

Discovery of (10 <i>R</i> )-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro- <i>2H</i> -8,4-(metheno)pyrazolo[4,3- <i>h</i> ][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations

Ted W. Johnson, Paul Richardson, Simon Bailey et al. · Journal of Medicinal Chemistry · 2014 · 585 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Pd-Catalyzed Alkyl to Aryl Migration and Cyclization:  An Efficient Synthesis of Fused Polycycles via Multiple C−H Activation

Qinhua Huang, Alessia Fazio, Guangxiu Dai et al. · Journal of the American Chemical Society · 2004 · 256 citations

Natural Sciences, Chemistry, Catalysis +14

Synthesis of Substituted Isoquinolines by Electrophilic Cyclization of Iminoalkynes

Qinhua Huang, Jack A. Hunter, Richard C. Larock · The Journal of Organic Chemistry · 2002 · 256 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

1,4-Palladium Migration via C−H Activation, Followed by Arylation:  Synthesis of Fused Polycycles

Marino A. Campo, Qinhua Huang, Tuanli Yao et al. · Journal of the American Chemical Society · 2003 · 234 citations

Natural Sciences, Chemistry, Catalysis +12

Synthesis of 4-(1-Alkenyl)isoquinolines by Palladium(II)-Catalyzed Cyclization/Olefination

Qinhua Huang, Richard C. Larock · The Journal of Organic Chemistry · 2002 · 170 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9