Paul Richardson

Key Green Chemistry research areas from a pharmaceutical manufacturers’ perspective revisited

Marian C. Bryan, Peter J. Dunn, David A. Entwistle et al. · Green Chemistry · 2018 · 601 citations · Full text

Natural Sciences, Chemical Engineering, Chemistry +17

Discovery of (10 <i>R</i> )-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro- <i>2H</i> -8,4-(metheno)pyrazolo[4,3- <i>h</i> ][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations

Ted W. Johnson, Paul Richardson, Simon Bailey et al. · Journal of Medicinal Chemistry · 2014 · 585 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

A platform for automated nanomole-scale reaction screening and micromole-scale synthesis in flow

Damith Perera, Joseph W. Tucker, Shalini Brahmbhatt et al. · Science · 2018 · 489 citations

Pharmacy, Chemical Engineering, Chemistry +17

Ligand-Accelerated <i>ortho</i>-C–H Alkylation of Arylcarboxylic Acids using Alkyl Boron Reagents

Peter Thuy-Boun, Giorgio Villa, Devin Dang et al. · Journal of the American Chemical Society · 2013 · 164 citations

Natural Sciences, Chemistry, Catalysis +9

Expanding Reactivity in DNA-Encoded Library Synthesis via Reversible Binding of DNA to an Inert Quaternary Ammonium Support

Dillon T. Flood, Shota Asai, Xue‐Jing Zhang et al. · Journal of the American Chemical Society · 2019 · 153 citations · Full text

Pharmacy, Biotechnology, Chemistry +12