Mary A. Brothers

Discovery of Ketone-Based Covalent Inhibitors of Coronavirus 3CL Proteases for the Potential Therapeutic Treatment of COVID-19

Robert L. Hoffman, Robert S. Kania, Mary A. Brothers et al. · Journal of Medicinal Chemistry · 2020 · 533 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +15

In Vitro Antiviral Activity and Single-Dose Pharmacokinetics in Humans of a Novel, Orally Bioavailable Inhibitor of Human Rhinovirus 3C Protease

Amy K. Patick, Mary A. Brothers, Fausto Maldonado et al. · Antimicrobial Agents and Chemotherapy · 2005 · 135 citations

Medicine, Pharmacokinetics, Pharmacology +17

The role of C3 fragments in endocytosis and extracellular cytotoxic reactions by polymorphonuclear leukocytes

Robert D. Schreiber, Michael K. Pangburn, Ann B. Bjornson et al. · Clinical Immunology and Immunopathology · 1982 · 70 citations

Life Sciences, Cell Biology, Immunology +16

Induction <i>in vitro</i> of a primary human antiviral cytotoxic T cell response

Andreas Cerny, P Fowler, Mary A. Brothers et al. · European Journal of Immunology · 1995 · 48 citations

Life Sciences, Immunology, Infectious Diseases +16

Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors

Peter S. Dragovich, Ru Zhou, Stephen E. Webber et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 43 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16