Concepedia

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

Mark E. Davis, Jonathan E. Zuckerman, Chung Hang Jonathan Choi, David B. Seligson, Anthony W. Tolcher, Christopher A. Alabi, Yun Yen, Jeremy D. Heidel, Antoni Ribas

Nature · 2010 · 2.5K citations · 21 references

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References

21

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

Andrew Fire, Siqun Xu, Mary K. Montgomery et al. · Nature · 1998 · 15.3K citations · Full text

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Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.4K citations

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RNA interference targeting Fas protects mice from fulminant hepatitis

Erwei Song, Sang‐Kyung Lee, Jie Wang et al. · Nature Medicine · 2003 · 1.1K citations

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RNA interference in adult mice

Anton P. McCaffrey, Leonard Meuse, Thu-Thao T. Pham et al. · Nature · 2002 · 1.1K citations

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The First Targeted Delivery of siRNA in Humans via a Self-Assembling, Cyclodextrin Polymer-Based Nanoparticle: From Concept to Clinic

Mark E. Davis · Molecular Pharmaceutics · 2009 · 966 citations

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