Concepedia

Gene Delivery

Gene delivery is the process of introducing exogenous DNA or RNA into host cells via delivery vectors to achieve therapeutic gene expression or genetic modification.

26.9K

Publications

1.9M

Citations

96.4K

Authors

8.3K

Institutions

Publications per year

2017–2026

5.7K

Variants

Gene Transfer

Parents

Children

Publications

26.9K

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

Otmane Boussif, Frank Lezoualc’h, Maria Antonietta Zanta et al. · Proceedings of the National Academy of Sciences · 1995 · 6.2K citations

, , +17

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

Philip L. Felgner, Thomas R. Gadek, Mai Marie Holm et al. · Proceedings of the National Academy of Sciences · 1987 · 5K citations · Full text

, , +15

In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector

Luigi Naldini, Ulrike Blömer, Philippe Gallay et al. · Science · 1996 · 4.9K citations

, , +14

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Lydia Alvarez‐Erviti, Yiqi Seow, HaiFang Yin et al. · Nature Biotechnology · 2011 · 4.8K citations

, , +12

Direct Gene Transfer into Mouse Muscle in Vivo

Jon A. Wolff, Robert W. Malone, Phillip Williams et al. · Science · 1990 · 4.2K citations

, , +16

1–5 of 26.9K

Authors

96.4K

  1. JM
    James M. Wilson

    University of Pennsylvania, United States

    214 publications · 28.9K citations

    96

    h-index

  2. EW
    Ernst Wagner

    Ludwig-Maximilians-Universität München, Germany

    165 publications · 18.5K citations

    70

    h-index

  3. KK
    Kazunori Kataoka

    The University of Tokyo, Japan

    112 publications · 11.4K citations

    65

    h-index

  4. RL
    Róbert Langer

    Massachusetts Institute of Technology, United States

    86 publications · 16.8K citations

    62

    h-index

  5. DT
    David T. Curiel

    University of Alabama at Birmingham, United States

    165 publications · 12.1K citations

    60

    h-index

1–5 of 96.4K

Institutions

8.3K

  1. University of Pennsylvania

    Philadelphia, United States

    132 h-index

    2.5K publications

    335.2K citations

  2. Harvard University

    Cambridge, United States

    124 h-index

    2K publications

    289K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    115 h-index

    3.2K publications

    228.1K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    114 h-index

    879 publications

    170.2K citations

  5. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    103 h-index

    1.2K publications

    143.1K citations

  6. Inserm

    Paris, France

    102 h-index

    3.2K publications

    262.8K citations

  7. University of Pittsburgh

    Pittsburgh, United States

    102 h-index

    1.5K publications

    142.2K citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    100 h-index

    1.1K publications

    203.6K citations

1–8 of 8.3K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 417 publications · 99.4K citations

    171

    h-index

  2. Molecular Therapy

    1.1K publications · 96.1K citations

    148

    h-index

  3. Human Gene Therapy

    1.2K publications · 80.3K citations

    133

    h-index

  4. Journal of Controlled Release

    822 publications · 69.6K citations

    130

    h-index

  5. Gene Therapy

    1.2K publications · 87.7K citations

    129

    h-index

1–5

See also

Gene Delivery

Delivery Vectors

Transfection Methods

Safety Challenges

Targeting Strategies

Cargo Types