Nicky Whalley

Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS

Sarah J. Ross, Alexey S. Revenko, Lyndsey Hanson et al. · Science Translational Medicine · 2017 · 175 citations

Processing of proglucagon to GLP-1 in pancreatic α-cells: is this a paracrine mechanism enabling GLP-1 to act on β-cells?

Nicky Whalley, L E Pritchard, David M. Smith et al. · Journal of Endocrinology · 2011 · 174 citations · Full text

High Glucose, Prohormone Convertase 2, Cellular Physiology +21

Targeted profiling of polar intracellular metabolites using ion-pair-high performance liquid chromatography and -ultra high performance liquid chromatography coupled to tandem mass spectrometry: Applications to serum, urine and tissue extracts

Filippos Michopoulos, Nicky Whalley, Georgios Theodoridis et al. · Journal of Chromatography A · 2014 · 91 citations

Polar Intracellular Metabolites, Biochemistry, Medicine +14

Pyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells

Antonio G. Trinidad, Nicky Whalley, Rachel Rowlinson et al. · Oncogene · 2017 · 30 citations · Full text

Cell Proliferation, Metabolic Remodeling, Cell Growth +20

Clinically Viable Gene Expression Assays with Potential for Predicting Benefit from MEK Inhibitors

Roz Brant, Alan Sharpe, Tom Liptrot et al. · Clinical Cancer Research · 2016 · 28 citations