Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors - Concepedia

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Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

304

Citations

29

References

2016

Year

Zachary Steinhart, Zvezdan Pavlovic, Megha Chandrashekhar, Traver Hart, Xiaowei Wang, Xiaoyu Zhang, Mélanie Robitaille, Kevin R. Brown, Sridevi Jaksani, René Overmeer,

Nature Medicine

Rnf43-mutant Pancreatic TumorsSignaling PathwayGenome-wide Crispr ScreensDruggable VulnerabilityCancer Cell BiologyCancer GenomicsGenome EngineeringCrisprGene EditingSystems BiologyMedicineCell BiologyGenome EditingTumor BiologyMolecular Signaling

References

	Year	Citations

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