René Overmeer

Sequential cancer mutations in cultured human intestinal stem cells

Jarno Drost, Richard H. van Jaarsveld, Bas Ponsioen et al. · Nature · 2015 · 1.1K citations · Full text

Life Sciences, Cell Biology, Oncology +14

Three DNA Polymerases, Recruited by Different Mechanisms, Carry Out NER Repair Synthesis in Human Cells

Tomoo Ogi, Siripan Limsirichaikul, René Overmeer et al. · Molecular Cell · 2010 · 382 citations · Full text

Life Sciences, Genetics, Molecular Biology +11

Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

Zachary Steinhart, Zvezdan Pavlovic, Megha Chandrashekhar et al. · Nature Medicine · 2016 · 319 citations

Life Sciences, Genetics, Molecular Biology +17

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening

Carla S. Veríssimo, René Overmeer, Bas Ponsioen et al. · eLife · 2016 · 270 citations · Full text

Medicine, Cancer Biology, Oncology +17

Sequential gene promoter methylation during HPV-induced cervical carcinogenesis

Florianne E Henken, Saskia M. Wilting, René Overmeer et al. · British Journal of Cancer · 2007 · 130 citations · Full text

Medicine, Molecular Biology, Molecular Genetics +17