Zachary Steinhart

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

Traver Hart, Megha Chandrashekhar, Michael Aregger et al. · Cell · 2015 · 1.8K citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

Zachary Steinhart, Zvezdan Pavlovic, Megha Chandrashekhar et al. · Nature Medicine · 2016 · 319 citations

Life Sciences, Genetics, Molecular Biology +17

CRISPR activation and interference screens decode stimulation responses in primary human T cells

Ralf Schmidt, Zachary Steinhart, Madeline Layeghi et al. · Science · 2022 · 316 citations · Full text

Life Sciences, Genetics, Immunology +17

Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer

Léo Aubert, Neethi Nandagopal, Zachary Steinhart et al. · Nature Communications · 2020 · 314 citations · Full text

Medicine, Molecular Biology, Oncology +16

Evaluation of SARS-CoV-2 serology assays reveals a range of test performance

Jeffrey D. Whitman, Joseph Hiatt, Cody T. Mowery et al. · Nature Biotechnology · 2020 · 299 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +12